Objective patients with early stage neuroendocrine cervical carcinoma necc have a high mortality rate despite aggressive therapy the rarity of this tumor precludes initiation of a randomized prospective trial we reviewed our experience in early stage disease and performed a meta analysis of the literature to identify prognostic factors and determine optimal multimodality therapymethods . 1 contrib gynecol obstet 1994191 11 multimodality therapy in gynecologic oncology sevin bu1 author information 1division of gynecologic oncology university of miami fla pmid 7995041 indexed for medline. A multicenter evaluation of sequential multimodality therapy and clinical outcome for the treatment of advanced endometrial cancer angeles alvarez secord x angeles alvarez secord search for articles by this author affiliations a gynecologic oncology group study j clin. We believe that this is in part due to multimodality therapy with surgery chemotherapy and radiation multi modality therapy is not a novel concept in the treatment of cervical nec 1 x 1 gardner gj reidy lagunes d and gehrig pa neuroendocrine tumors of the gynecologic tract a society of gynecologic oncology sgo clinical document. In a multicenter study conducted by the southwest oncology group swog 26 patients with metastatic penile cancer received single agent cisplatin at a dosage of 50 mg m 2 on days 1 and 8 of each 28 day cycle only four patients 15 experienced responses that persisted for 1 3 months
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