Pediatric drug formulations a review of challenges and progress article literature review pdf available in pediatrics 1342 july 2014 with 7065 reads how we measure reads. Children differ from adults in many aspects of pharmacotherapy including capabilities for drug administration medicine related toxicity and taste preferences it is essential that pediatric medicines are formulated to best suit a childs age size physiologic condition and treatment requirements to ensure adequate treatment of all children different routes of administration dosage . 1 introduction pediatric patients require different oral drug delivery systems than other subsets of the population due to their continuing development hence dosing and administration requirements conventional formulations are not designed for this patient group thus manipulation and compounding has become common practice age appropriate oral drug delivery systems specifically developed . The development of an appropriate pediatric formulation is a complex task that requires multiple considerations therefore it is appropriate that drug developers consider possible pediatric formulations early in the drug development process a natural point in time would be at the same time a solid oral form is being considered for adults. Paediatric drug product development various formulation networks also exist european paediatric formulation initiative eupfi united states paediatric formulation i nitiative uspfi global research in paediatrics grip work package 5 paediatric formulations iq consortium pediatric working group
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